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Altius Institute

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FORGE2 standalone was developed by Charles Breeze at UCL as part of the EpiTrain Initial Training Network.
FORGE2 is the latest iteration of the FORGE tool originally developed by Ian Dunham.
The web interface was originally developed by Javier Herrero from the Bill Lyons Informatics Centre team and updated by Alex Reynolds from the Altius Institute for Biomedical Sciences in Seattle.
The example data set corresponds to a set of PR associated SNPs from the GWAS catalog.
FORGEdb standalone and web were developed by Charles Breeze at NCI DCEG.

(last updated on Thu Jan 11 12:04:35 2024)


FORGE2 is currently running on a virtual machine provided by the Altius Institute for Biomedical Sciences.


Email Charles Breeze: c.breeze(at)


Breeze, CE, Haugen, E, Reynolds, A, Teschendorff, A, van Dongen, J, Lan, Q, Rothman, N, Bourque, G, Dunham, I, Beck, S, Stamatoyannopoulos J, Franceschini, N, Berndt, SI (2022). Integrative analysis of 3604 GWAS reveals multiple novel cell type-specific regulatory associations. Genome Biology 23, 13. doi: 10.1186/s13059-021-02560-3
Breeze, C.E., Haugen, E., Gutierrez-Arcelus, M., Yao, X., Teschendorff, A., Beck, S., Dunham, I., Stamatoyannopoulos, J., Franceschini, N., Machiela, M., Berndt, S. (2022). FORGEdb: systematic analysis of candidate causal variants to uncover target genes and mechanisms in complex traits. bioRxiv 2022.11.14.516365. doi: 10.1101/2022.11.14.516365